Tomographic volume and 3D rendering of the neuronal polyGA aggregate inside a cell

Poly-GA ribbons (red), 26S proteasomes (green), ribosomes (yellow), TRiC/CCT chaperonins (purple). Rat neurons were cultured on EM grids and thinned with in a cryo-FIB. The tomographic tilt series was acquired in a cryo-TEM.